Ciba Foundation Symposium - Bilharziasis
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Ciba Foundation Symposium : Bilharziasis held in commemoratiion of theodor Maximilian Bilharz
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The paper considers a model for the transmission of bilharzia based on Macdonald's assumptions, in the light of data observed in the field. It is shown, in particular, that the threshold parameter governing whether or not an endemic cycle can be established is closely related to the proportion of infected snails in a community, and that this proportion is normally observed to be rather smaller than is compatible with the model. By considering more sophisticated models, allowing for the latent period of infection in the snails, and also for spatial and seasonal heterogeneity, the effective proportion of infected snails, from the point of view of Macdonald's model, is shown to be rather larger, and expressions are given whereby it can be evaluated from observable quantities.
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However, for the data from Malirong which are taken as illustration, it is also demonstrated that an even more plausible threshold value is obtained from a simple model incorporating human immunity in addition to the assumptions of Macdonald's model, and that, if this model were reasonable, human immunity would appear to be the most important factor in controlling the level of the disease in Malirong. Most users should sign in with their email address. If you originally registered with a username please use that to sign in.
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Sign In or Create an Account. Sign In. Advanced Search. Article Navigation. Close mobile search navigation Article Navigation. Volume Macdonald's model and the transmission of bilharzia Andrew D. Gonville and Caius College, Cambridge, U. Oxford Academic. Google Scholar. Cite Citation. Permissions Icon Permissions. Abstract The paper considers a model for the transmission of bilharzia based on Macdonald's assumptions, in the light of data observed in the field.
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